On Friday, receiver Mike Evans (hamstring) was ruled out. In addition, five Buccaneers were listed as questionable including safety Jordan Whitehead (quad), nose tackle Greg Gaines (calf), safety Tykee Smith (knee), receiver Jalen McMillan (hamstring) and long snapper Evan Deckers (hamstring).
DNP: Did Not Participate
FP: Full Participation
LP: Limited Participation
Read below for the full injury report for both teams:
Buccaneers
- G Ben Bredeson (shoulder) - LP (Wed.), LP (Thurs.), FP (Friday)
- LS Evan Deckers (hamstring) - FP (Wed.), FP (Thurs.), FP (Friday) Game Status: Questionable
- WR Mike Evans (hamstring) - DNP (Wed.), DNP (Thurs.), DNP (Friday) Game Status: Out
- NT Greg Gaines (calf) - LP (Wed.), LP (Thurs.), FP (Friday) Game Status: Questionable
- DL William Gholston (knee/ribs) - LP (Wed.), LP (Thurs.), LP (Friday)
- RB Bucky Irving (toe) - LP (Wed.), LP (Thurs.), FP (Friday)
- S Tykee Smith (knee) - LP (Friday) Game Status: Questionable
- QB Baker Mayfield (toe) - DNP (Wed.), DNP (Thurs.), LP (Friday)
- WR Jalen McMillan (hamstring) - DNP (Wed.), DNP (Thurs.), LP (Friday) Game Status: Questionable
- LB J.J. Russell (ribs) - LP (Wed.), LP (Thurs.), FP (Friday)
- WR Sterling Shepard (hamstring/hip) - DNP (Wed.), DNP (Thurs.), LP (Friday)
- NT Vita Vea (hip) - LP (Wed.), LP (Thurs.), LP (Friday)
- S Jordan Whitehead (quad) - DNP (Wed.), DNP (Thurs.), LP (Friday) Game Status: Questionable
49ers
- DL Nick Bosa (hip) - LP (Wed.), LP (Thurs.), LP (Friday) Game Status: Questionable
- WR Chris Conley (hamstring) - DNP (Wed.), DNP (Thurs.), DNP (Friday) Game Status: Out
- C Jon Feliciano (knee) - LP (Wed.), LP (Thurs.), LP (Friday) Game Status: Questionable
- DL Kevin Givens (groin) - DNP (Wed.), DNP (Thurs.), DNP (Friday) Game Status: Out
- CB Renardo Green (ankle) - FP (Wed.), FP (Thurs.), FP (Friday)
- DE Yetur Gross-Matos (knee) - LP (Wed.), LP (Thurs.), LP (Friday) Game Status: Out
- WR Jauan Jennings (hip) - LP (Wed.), LP (Thurs.), LP (Friday)
- RB Jordan Mason (shoulder) - FP (Wed.), LP (Thurs.), LP (Friday)
- RB Christian McCaffrey (achilles) - LP (Wed.), LP (Thurs.), LP (Friday) Game Status: Questionable
- K Jake Moody (right ankle) - LP (Wed.), LP (Thurs.), LP (Friday)
- S Malik Mustapha (calf) - LP (Thurs.), LP (Friday) Game Status: Questionable
- WR Deebo Samuel (rib/oblique) - LP (Wed.), ), LP (Thurs.), LP (Friday) Game Status: Questionable
- CB Charvarius Ward (personal) - DNP (Wed.), DNP (Thurs.), DNP (Friday) Game Status: Out
- T Trent Williams (rest) - DNP (Wed.), FP (Thurs.), FP (Friday)
- LB Dee Winters (concussion) - FP (Wed.), FP (Thurs.), FP (Friday)
- P Mitch Wishnowsky (back) - LP (Wed.), LP (Thurs.), LP (Friday)